Instituto Nacional de Bioinformática

Post-Doctoral Researcher and Technician in Functional Bioinformatics

The Centro Nacional de Análisis Genómico (CNAG) at the Barcelona Science Park (PCB) opens a position for A Post-Doctoral Researcher and a Technician in Functional Bioinformatics
Ref: FBI-120426

The Functional Bioinformatics (FBI) group led by Dr. Michael Sammeth at the CNAG in Barcelona (http://fbi.sammeth.net) is looking for talented candidates who are highly motivated for cutting-edge research in functional genomics and transcriptomics, involving data produced by the latest Next-Generation Sequencing (NGS) technologies.
The FBI group investigates functional aspects of expressed genes, as by their mutual interaction and regulation, to advance in the understanding how the information encoded in a single genome can give rise to a plethora of different cell types that together form an organism.
To achieve these ambitious goals, we employ results of state-of-the-art sequencing experiments applied to the transcriptome (RNA-Seq) and from Chip-Seq assays, most of them carried out at the CNAG (http://www.cnag.eu).
With currently twelve state-of-the-art Illumina HiSeq sequencing machines, the CNAG centre is becoming one of the major high throughput Sequencing Centers in Europe, participating in several consortia of networked projects such as the International Cancer Genome Consortium, and EUfunded projects such as READNA, ESGI, GEUVADIS and BLUEPRINT.

Responsibilities
The successful candidate will be involved in different projects and collaborations, and explore various aspects of data yielded by deep sequencing in order to advance in our understanding about functionality of genomic elements. To this end, the candidate will primarily apply established pipelines to RNASeq and Chip-Seq datasets.
Depending on the candidate’s profile, the FBI also offers the possibility to participate actively in the development of computational approaches for analyzing NGS data, based on the programs Flux Capacitor / Simulator, and Astalavista we have developed.

Candidate profile:
We are looking for a post-doctorate research fellow and a technician with a PhD/Master’s Degree in Biology, Bioinformatics, or related fields.
The CNAG operates a powerful Unix cluster with currently ~1000 cores and 2 Petabyte of disk space; therefore, a profound knowledge of common Unix commands is an essential pre-requirement for the candidate to be eligible. Candidates are also expected to possess a background that provided them with a general knowledge about the biological concepts of gene expression.
The successful candidate will employ statistical frameworks (e.g., the “R” platform) and scripting to pursue comparisons of experimental data. The FBI group already developed pipelines for the low-level data processing, and we support candidates who are interested in extending and improving these computational tools implemented in Java and Groovy.
In addition to these technical skills, we especially encourage candidates with preliminary experiences in genomics, transcriptomics, and/or the analysis of high throughput sequencing data to apply.

Conditions:
We offer a 2-year contract is offered with prospective starting date in june/july or september 2012. Salary will be determined according to the academical degree and experience of the candidate.

Application procedure:
Interested candidates should send their CV to msammeth@pcb.ub.es